Primo: Why it has become the GOAT in recent times?

Firstly, thank you for subscribing! Each week, we will dive into a new topic - all things bodybuilding.

We are kicking off our first newsletter with Primobolan (Primo). By the end of this newsletter you will have a better understanding of the medical uses for Primo, its mechanism of action for bodybuilders and the concerns to note for usage.

I hope you find this information useful and if you do, please let me know!

What is Primobolan (Methenolone)?

Methenolone, also known as Primobolan, is popular in both the medical and bodybuilding world and is available in oral (Methenolone acetate) and injectable (Methenolone enanthate) forms.

Medical Uses

Medically, Primo has been used to treat conditions such as:

Chronic wasting diseases

Severe infections

Recovery from surgery

Osteoporosis

When it comes to ‘assistance’ selection, the key thing I want to know is if it has been tested clinically on humans. Personally, I opt to stay away from ‘assistance’ that have only been trialled on animals. It’s worth noting that if drugs have gone through human trials, it doesn’t mean its a green light and risk free, but it does offer valuable information in terms of dosages and highlights anything we should be looking out for.

If you ever want to learn more about any compound I recommend using https://pubmed.ncbi.nlm.nih.gov/ . This is where studies conducted are logged.

Mechanism of Action
Mechanism of action = how it works and what can we gain from it.

Anabolic Effects:

As with all ‘assistance’, Primo binds to androgen receptors in the body, which are found in muscle tissue, bones, and other organs. When it binds to these receptors, it enhances protein synthesis, the more protein synthesis we can get = more muscle we can build.

This anabolic effect is the primary reason for its use in muscle wasting diseases and performance enhancement.

1.Reduced Catabolism:

As bodybuilders one of the worst things we can do is become catabolic. Primo helps prevent exactly that with its ability to reduce protein breakdown.

2.Enhanced Nitrogen Retention:

Nitrogen plays a huge role in our ability to grow new muscle and Primo improves the body’s nitrogen balance. Having a positive nitrogen balance indicates that muscle tissues are being built rather than broken down.

3.Non-Aromatising:

Primo does not convert to oestrogen in the body, which means it doesn’t cause the dreaded gyno.

4.Minimal Androgenic Activity:

Compared to other ‘assistance’, Primo has lower (but not totally zero) androgenic activity. Which means a lesser risk to side effects relating to masculinisation. However, I know females who have had issues on dosages as low as 50mg per week.

Health Concerns

1. Cardiovascular Issues

Hypertension (increase blood pressure).

Lipid Profile (Cholesterol): It can reduce HDL (good) cholesterol levels and increase LDL (bad) cholesterol levels, which can lead to atherosclerosis and increase the risk of heart disease and stroke.

2. Liver Toxicity

While Primo is considered to have less hepatotoxicity compared to other ‘assistance’ prolonged use can still lead to liver damage or liver disease.

3. Skin and Hair Issues

Acne: Increased oil production in the skin can lead to acne.

Hair Loss: accelerated male pattern baldness in individuals genetically predisposed to hair loss.

4. Other Potential Risks

Kidney Damage: There is potential for kidney damage with prolonged use.

Immune System Suppression: Some studies suggest that anabolic steroids can suppress the immune system.

As with all ‘assistance’ fertility can be negatively impacted with changes to mental state.

Supplements

Taking supplements does not mean being ignorant to tracking your health markers, however some supplements have been formulated with the above in mind and can be found below.

Code SNB10 will get you 10% off.

https://www.supplementneeds.co.uk/products/liver-heart-kidney-and-blood-pressure-stack-bundle

These can also be purchased as stand alone products but buying in a bundle discounts the cost.

Have a great weekend and catch up next week for #002!

Lewy Blackmore

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